Argonaute database | Tool name | Argonaute database |
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| URL | 1. http://www.umm.uni-heidelberg.de/apps/zmf/mirwalk/ 2. http://www.ma.uni-heidelberg.de/apps/zmf/argonaute/interface |
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| Important features | Provides information on mammalian microRNAs, their coding regions and regulatory aspects of their targeted genes. |
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| Citations | Shahi P, Loukianiouk S, Bohne-Lang A, Kenzelmann M, KFCffer S, Maertens S, Eils
R, GrF6ne HJ, Gretz N, Brors B. Argonaute--a database for gene regulation by
mammalian microRNAs. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D115-8.
PubMed PMID: 16381827; PubMed Central PMCID: PMC1347455.
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| Year of publication | 2006 |
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| Rank by usage frequency | 100 |
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| Comments | The ARGONAUTE database has been incorporated in a new internet-based resource called miRWalk. |
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| Function | FUNCTIONAL ANALYSIS: regulation/ expression, SPECIES: rat, SPECIES: mouse, 1. http://www.umm.uni-heidelberg.de/apps/zmf/mirwalk/ 2. http://www.ma.uni-heidelberg.de/apps/zmf/argonaute/interface, Provides information on mammalian microRNAs- their coding regions and regulatory aspects of their targeted genes., Shahi P- Loukianiouk S- Bohne-Lang A- Kenzelmann M- KFCffer S- Maertens S- Eils
R- GrF6ne HJ- Gretz N- Brors B. Argonaute--a database for gene regulation by
mammalian microRNAs. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D115-8.
PubMed PMID: 16381827; PubMed Central PMCID: PMC1347455.
, 2006, 100, The ARGONAUTE database has been incorporated in a new internet-based resource called miRWalk., Online, I. SPECIES SUPPORTED INCLUDE: human- mouse and rat . II. QUERY OR INPUT DATA: 1. Gene list (single/ multiple) 2. Select gene region: promoter- 3' UTR- 5' UTR- CDS 3. Other options: transcript length- seed region- p value 4. Choose among 8 target prediction tools III. OUTPUT DATA: depending on the type of analysis chosen the output could depict:1. MiRNA-targets interactions using miRWalk algorithm on the complete sequence (promoter- 5' UTR- CDS and 3' UTR) 3. MiRNA-target predictions by RNA22- miRanda- miRDB- TargetScan- RNAhybrid- PITA- PICTAR- and Diana-microT 4. Genes involved in human physiological pathways and OMIM disorders 5. Mitochondrial target predictions for human- mouse and rat 6. Proteins that play a role in microRNA processing. IV. ADDITIONAL INFORMATION: It currently houses information on 839 miRNAs from human- mouse and rat., Identify whether a given precursor sequence is a true or pseudo candidate. |
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